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Comparative analytical performance of targeted NGS panels for solid tumour biomarker reporting

Nair P, Ortiz M, Haddad A

Molecular Pathology Journal · Published 24 Jun 2026 · DOI: 10.00000/mpj.2026.0061

Abstract

We compared four targeted next-generation sequencing panels across 620 solid tumour specimens for variant detection concordance, limit of detection, copy number calling and turnaround time, with attention to specimen quality thresholds and reporting implications for low tumour cellularity samples.

Keywords

NGSbiomarkersanalytical validationsolid tumours

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Cite this article

Nair P, Ortiz M, Haddad A. Comparative analytical performance of targeted NGS panels for solid tumour biomarker reporting. Molecular Pathology Journal. 2026. doi:10.00000/mpj.2026.0061