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Diagnostic pitfalls in metastatic carcinoma of unknown primary: a case-based approach

Weber S, Nair P

Global Pathology Review · Published 11 Jun 2026 · DOI: 10.00000/gpr.2026.0219

Abstract

A structured immunohistochemical approach to carcinoma of unknown primary is illustrated through three instructive cases, highlighting antibody panel selection, interpretation traps and the contribution of molecular site-of-origin assays.

Keywords

CUPimmunohistochemistrydiagnostic pitfalls

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Introduction

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Methods

Study design, data sources, inclusion criteria, statistical analysis and ethical approval are reported in full in the published version.

Results

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Discussion

Interpretation, limitations and implications for practice are presented in the published version.

References

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Cite this article

Weber S, Nair P. Diagnostic pitfalls in metastatic carcinoma of unknown primary: a case-based approach. Global Pathology Review. 2026. doi:10.00000/gpr.2026.0219