Demonstration viewer. The production library streams anonymised, appropriately licensed whole-slide images with pan, zoom, measurement and annotation tools.
Clinical history
66-year-old with PSA 8.4 ng/mL.
Specimen
Transperineal targeted biopsy · Stain: H&E
Microscopic description
Infiltrative small glands with prominent nucleoli and absent basal cells, with a minority component of fused and poorly formed glands.
Diagnostic question
What percentage of pattern 4 is present and how does it affect the grade group?
Reveal differential diagnosis
Atypical small acinar proliferation
Adenosis
High-grade prostatic intraepithelial neoplasia
Reveal final diagnosis
Acinar adenocarcinoma, Gleason score 3+4=7, Grade Group 2
Learning points
Report percentage of pattern 4
Assess perineural invasion and core involvement
Basal cell markers help exclude mimics
Self-assessment
Member feature. Self-assessment, case notes and progress tracking are available to members. See benefits.
All whole-slide images in this library are anonymised and used under appropriate licence. Cases are provided for education only and must not be used for clinical diagnosis.