Demonstration viewer. The production library streams anonymised, appropriately licensed whole-slide images with pan, zoom, measurement and annotation tools.
Clinical history
70-year-old former smoker with a subsolid nodule on CT.
Specimen
Lobectomy · Stain: H&E and TTF-1
Microscopic description
Neoplastic cells growing along intact alveolar septa with a focal acinar invasive component measuring 7 mm.
Diagnostic question
How is invasive size determined and why does it matter?
Reveal differential diagnosis
Adenocarcinoma in situ
Minimally invasive adenocarcinoma
Reactive pneumocyte hyperplasia
Reveal final diagnosis
Invasive adenocarcinoma, lepidic predominant
Learning points
Staging uses invasive size, not total tumour size
Record growth pattern percentages
Assess pleural and lymphovascular invasion
Self-assessment
Member feature. Self-assessment, case notes and progress tracking are available to members. See benefits.
All whole-slide images in this library are anonymised and used under appropriate licence. Cases are provided for education only and must not be used for clinical diagnosis.